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AMPK Inhibits the Stimulatory Effects of TGF-β on Smad2/3 Activity, Cell Migration, and Epithelial-to-Mesenchymal Transition
AMP-activated protein kinase (AMPK), an important downstream effector of the tumor suppressor liver kinase 1 (LKB1) and pharmacologic target of metformin, is well known to exert a preventive and inhibitory effect on tumorigenesis; however, its role in cancer progression and metastasis has not been w...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Pharmacol |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658597/ https://ncbi.nlm.nih.gov/pubmed/26424816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.099549 |
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