Negative regulation of Bmi-1 by AMPK and implication in cancer progression

Bmi-1 is a transcriptional regulator that promotes tumor cell self-renewal and epithelial to mesenchymal transition and its upregulation is associated with tumor progression, AMPK is an intracellular fuel-sensing enzyme and plays important roles in tumor cell growth and progression. Thus, the presen...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Huang, Deqiang, He, Xiaoling, Zou, Junrong, Guo, Pei, Jiang, Shanshan, Lv, Nonghua, Alekseyev, Yuriy, Luo, Lingyu, Luo, Zhijun
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868749/
https://ncbi.nlm.nih.gov/pubmed/26717043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6748
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