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Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway
Glycoproteins and non-glycoproteins possessing unfolded/misfolded parts in their luminal regions are cleared from the endoplasmic reticulum (ER) by ER-associated degradation (ERAD)-L with distinct mechanisms. Two-step mannose trimming from Man(9)GlcNAc(2) is crucial in the ERAD-L of glycoproteins. W...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657166/ https://ncbi.nlm.nih.gov/pubmed/26572623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201504109 |
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