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The Crucial Role of Demannosylating Asparagine-Linked Glycans in ERADicating Misfolded Glycoproteins in the Endoplasmic Reticulum

Most membrane and secreted proteins are glycosylated on certain asparagine (N) residues in the endoplasmic reticulum (ER), which is crucial for their correct folding and function. Protein folding is a fundamentally inefficient and error-prone process that can be easily interfered by genetic mutation...

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Detalhes bibliográficos
Publicado no:Front Plant Sci
Main Authors: Zhang, Jianjun, Wu, Jiarui, Liu, Linchuan, Li, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835635/
https://ncbi.nlm.nih.gov/pubmed/33510762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2020.625033
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