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PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence
Promyelocytic leukemia protein (PML) nuclear bodies (NBs) recruit multiple partners, including p53 and many of its regulators. NBs are believed to facilitate several posttranslational modifications and are key regulators of senescence. PML, the organizer of NBs, is expressed as a number of splice va...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655504/ https://ncbi.nlm.nih.gov/pubmed/26578773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507540112 |
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