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Acute promyelocytic leukemia, arsenic, and PML bodies

Acute promyelocytic leukemia (APL) is driven by a chromosomal translocation whose product, the PML/retinoic acid (RA) receptor α (RARA) fusion protein, affects both nuclear receptor signaling and PML body assembly. Dissection of APL pathogenesis has led to the rediscovery of PML bodies and revealed...

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Bibliografske podrobnosti
Main Authors: de Thé, Hugues, Le Bras, Morgane, Lallemand-Breitenbach, Valérie
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392943/
https://ncbi.nlm.nih.gov/pubmed/22778276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112044
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