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Acute promyelocytic leukemia, arsenic, and PML bodies
Acute promyelocytic leukemia (APL) is driven by a chromosomal translocation whose product, the PML/retinoic acid (RA) receptor α (RARA) fusion protein, affects both nuclear receptor signaling and PML body assembly. Dissection of APL pathogenesis has led to the rediscovery of PML bodies and revealed...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392943/ https://ncbi.nlm.nih.gov/pubmed/22778276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112044 |
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