Llwytho...

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus.

The PML protein, identified first as part of the oncogenic PML-RARalpha chimera in acute promyelocytic leukemia (APL), concentrates within discrete subnuclear structures, corresponding to some types of nuclear bodies. These structures are disrupted in APL cells, and retinoic acid (RA) can trigger th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Müller, S, Matunis, M J, Dejean, A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170358/
https://ncbi.nlm.nih.gov/pubmed/9427741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.1.61
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