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Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus.

The PML protein, identified first as part of the oncogenic PML-RARalpha chimera in acute promyelocytic leukemia (APL), concentrates within discrete subnuclear structures, corresponding to some types of nuclear bodies. These structures are disrupted in APL cells, and retinoic acid (RA) can trigger th...

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Bibliografski detalji
Glavni autori: Müller, S, Matunis, M J, Dejean, A
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170358/
https://ncbi.nlm.nih.gov/pubmed/9427741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.1.61
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