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Characterization of kappa opioid receptor mediated, dynorphin-stimulated [(35)S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting
Differential modulation of kappa opioid receptor (KOR) signaling has been a proposed strategy for developing therapies for drug addiction and depression by either activating or blocking this receptor. Hence, there have been significant efforts to generate ligands with diverse pharmacological propert...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Neuropharmacology |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655192/ https://ncbi.nlm.nih.gov/pubmed/26160155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.07.001 |
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