Chronic treatment with varenicline changes expression of four nAChR binding sites in mice

INTRODUCTION: Chronic treatment with nicotine is known to increase the α4β2-nAChR sites in brain, to decrease α6β2-nAChR sites and to have minimal effect on α3β4- and α7-nAChR populations. Varenicline is now used as a smoking cessation treatment, with and without continued smoking or nicotine replac...

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Publicado no:Neuropharmacology
Main Authors: Marks, Michael J., O’Neill, Heidi C., Wynalda-Camozzi, Kelly M., Ortiz, Nick C., Simmons, Emily E., Short, Caitlin A., Butt, Christopher M., McIntosh, J. Michael, Grady, Sharon R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655142/
https://ncbi.nlm.nih.gov/pubmed/26192545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.07.019
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