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Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA

The α9α10 nicotinic acetylcholine receptor (nAChR) may be a potential target in pathophysiology of the auditory system, chronic pain and breast and lung cancers. Alpha-conotoxins, from the predatory marine snail Conus, are potent nicotinic antagonists, some of which are selective for the α9α10 nAChR...

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Bibliografski detalji
Glavni autori: Azam, Layla, McIntosh, J Michael
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433650/
https://ncbi.nlm.nih.gov/pubmed/22774872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07867.x
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