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Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA
The α9α10 nicotinic acetylcholine receptor (nAChR) may be a potential target in pathophysiology of the auditory system, chronic pain and breast and lung cancers. Alpha-conotoxins, from the predatory marine snail Conus, are potent nicotinic antagonists, some of which are selective for the α9α10 nAChR...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433650/ https://ncbi.nlm.nih.gov/pubmed/22774872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07867.x |
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