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α–RgIA, a Novel Conotoxin that Blocks the α9α10 nAChR: Structure and Identification of Key Receptor Binding Residues
α-Conotoxins are small disulfide-constrained peptides from cone snails which act as antagonists at specific subtypes of nicotinic acetylcholine receptors (nAChRs). The 13-residue peptide α-RgIA is a member of the α-4,3 family of α-conotoxins and selectively blocks the α9α10 nAChR subtype, in contras...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376044/ https://ncbi.nlm.nih.gov/pubmed/18295795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.082 |
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