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Density of α4β2* nAChR on the surface of neurons is modulated by chronic antagonist exposure

The expression of high-affinity α4β2* nicotinic acetylcholine receptors (nAChR) increases following chronic exposure to nicotinic agonists. While, nAChR antagonists can also produce upregulation, these changes are often less pronounced than achieved with agonists. It is unknown if nAChR agonists and...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Zambrano, Cristian A, Short, Caitlin A, Salamander, Rakel M, Grady, Sharon R, Marks, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324685/
https://ncbi.nlm.nih.gov/pubmed/25729578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.111
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