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Density of α4β2* nAChR on the surface of neurons is modulated by chronic antagonist exposure

The expression of high-affinity α4β2* nicotinic acetylcholine receptors (nAChR) increases following chronic exposure to nicotinic agonists. While, nAChR antagonists can also produce upregulation, these changes are often less pronounced than achieved with agonists. It is unknown if nAChR agonists and...

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Опубликовано в: :Pharmacol Res Perspect
Главные авторы: Zambrano, Cristian A, Short, Caitlin A, Salamander, Rakel M, Grady, Sharon R, Marks, Michael J
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324685/
https://ncbi.nlm.nih.gov/pubmed/25729578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.111
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