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Igs as Substrates for Transglutaminase 2: Implications for Autoantibody Production in Celiac Disease
Autoantibodies specific for the enzyme transglutaminase 2 (TG2) are a hallmark of the gluten-sensitive enteropathy celiac disease. Production of the Abs is strictly dependent on exposure to dietary gluten proteins, thus raising the question how a foreign Ag (gluten) can induce an autoimmune response...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
AAI
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654229/ https://ncbi.nlm.nih.gov/pubmed/26503953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501363 |
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