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Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease
Antibodies to the autoantigen transglutaminase 2 (TG2) are a hallmark of celiac disease. We have studied the interaction between TG2 and an anti-TG2 antibody (679-14-E06) derived from a single gut IgA plasma cell of a celiac disease patient. The antibody recognizes one of four identified epitopes ta...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4571865/ https://ncbi.nlm.nih.gov/pubmed/26160175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669895 |
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