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Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron–sulfur protein

Mitochondria play an important role in numerous diseases as well as normative aging. Severe reduction in mitochondrial function contributes to childhood disorders such as Leigh Syndrome, whereas mild disruption can extend the lifespan of model organisms. The Caenorhabditis elegans isp-1 gene encodes...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Jafari, Gholamali, Wasko, Brian M., Tonge, Ashley, Schurman, Nathan, Dong, Cindy, Li, Zhongyu, Peters, Rebecca, Kayser, Ernst-Bernhard, Pitt, Jason N., Morgan, Phil G., Sedensky, Margaret M., Crofts, Antony R., Kaeberlein, Matt
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653183/
https://ncbi.nlm.nih.gov/pubmed/26504246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509416112
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