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New functional and biophysical insights into the mitochondrial Rieske iron-sulfur protein from genetic suppressor analysis in C. elegans

Several intragenic mutations suppress the C. elegans isp-1(qm150) allele of the mitochondrial Rieske iron-sulfur protein (ISP), a catalytic subunit of Complex III of the respiratory chain. These mutations were located in a helical region of the “tether” span of ISP-1, distant from the primary mutati...

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Détails bibliographiques
Publié dans:Worm
Auteurs principaux: Jafari, Gholamali, Wasko, Brian M., Kaeberlein, Matt, Crofts, Antony R.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911972/
https://ncbi.nlm.nih.gov/pubmed/27383074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21624054.2016.1174803
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