AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

AF1q is an MLL fusion partner that was identified from acute myeloid leukemia (AML) patients with t (1; 11) (q21; q23) chromosomal abnormality. The function of AF1q is not yet fully known, however, elevated AF1q expression is associated with poor clinical outcomes in various malignancies. Here, we s...

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Pubblicato in:Oncotarget
Autori principali: Park, Jino, Schlederer, Michaela, Schreiber, Martin, Ice, Ryan, Merkel, Olaf, Bilban, Martin, Hofbauer, Sebastian, Kim, Soojin, Addison, Joseph, Zou, Jie, Ji, Chunyan, Bunting, Silvia T., Wang, Zhengqi, Shoham, Menachem, Huang, Gang, Bago-Horvath, Zsuzsanna, Gibson, Laura F., Rojanasakul, Yon, Remick, Scot, Ivanov, Alexey, Pugacheva, Elena, Bunting, Kevin D., Moriggl, Richard, Kenner, Lukas, Tse, William
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653036/
https://ncbi.nlm.nih.gov/pubmed/26079538
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