MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling

Constitutive STAT3 activation by tyrosine phosphorylation of mutated or amplified tyrosine kinases (pYSTAT3) is critical for cancer initiation, progression, invasion, and motility of carcinoma cells. We showed that AF1q is associated with STAT3 signaling in breast cancer cells. In xenograft models,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Jino, Kim, Soojin, Joh, Joongho, Remick, Scot C., Miller, Donald M., Yan, Jun, Kanaan, Zeyad, Chao, Ju-Hsien, Krem, Maxwell M., Basu, Soumit K., Hagiwara, Shotaro, Kenner, Lukas, Moriggl, Richard, Bunting, Kevin D., Tse, William
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190071/
https://ncbi.nlm.nih.gov/pubmed/27259262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9759
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