Pro-metastatic NEDD9 regulates individual cell migration via caveolin-1-dependent trafficking of integrins

Por Kozyulina, Polina Y., Loskutov, Yuriy V., Kozyreva, Varvara K., Rajulapati, Anuradha, Ice, Ryan J., Jones, Brandon. C., Pugacheva, Elena N.
Publicado no Mol Cancer Res (2014)

NEDD9 depletion destabilizes Aurora A kinase and heightens the efficacy of Aurora A inhibitors: implications for treatment of metastatic solid tumors

Por Ice, Ryan J., McLaughlin, Sarah L., Livengood, Ryan H., Culp, Mark V., Eddy, Erik R., Ivanov, Alexey V., Pugacheva, Elena N.
Publicado em 2013

“NEDD9 Regulates Actin Dynamics through Cortactin Deacetylation in an AURKA/HDAC6-dependent Manner”

Por Kozyreva, Varvara K., McLaughlin, Sarah L., Livengood, Ryan H., Calkins, Robin A., Kelley, Laura C., Rajulapati, Anuradha, Ice, Ryan J., Smolkin, Matthew B., Weed, Scott A., Pugacheva, Elena N.
Publicado em 2014

NEDD9/Arf6-Dependent Endocytic Trafficking of Matrix Metalloproteinase 14: A Novel Mechanism for Blocking Mesenchymal Cell Invasion and Metastasis of Breast Cancer

Por Loskutov, Yuriy V., Kozyulina, Polina Y., Kozyreva, Varvara K., Ice, Ryan J., Jones, Brandon C., Roston, Trevor J., Smolkin, Matthew B., Ivanov, Alexey V., Wysolmerski, Robert B., Pugacheva, Elena N.
Publicado no Oncogene (2014)

“NEDD9 Depletion Leads to MMP14 Inactivation by TIMP2 and Prevents Invasion and Metastasis.”

Por McLaughlin, Sarah L., Ice, Ryan J., Rajulapati, Anuradha, Kozyulina, Polina Y., Livengood, Ryan H., Kozyreva, Varvara K., Loskutov, Yuriy V., Culp, Mark V., Weed, Scott A., Ivanov, Alexey V., Pugacheva, Elena N.
Publicado em 2013

Combination of eribulin and Aurora A inhibitor MLN8237 prevents metastatic colonization and induces cytotoxic autophagy in breast cancer

Por Kozyreva, Varvara K., Kiseleva, Anna A., Ice, Ryan J., Jones, Brandon C., Loskutov, Yuriy V., Matalkah, Fatimah, Smolkin, Matthew B., Marinak, Kristina, Livengood, Ryan H., Salkeni, Mohamad A., Wen, Sijin, Hazard, Hannah W., Layne, Ginger P., Walsh, Callee M., Cantrell, Pamela S., Kilby, Greg W., Mahavadi, Sricharan, Shah, Neal, Pugacheva, Elena N.
Publicado no Mol Cancer Ther (2016)

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

Por Park, Jino, Schlederer, Michaela, Schreiber, Martin, Ice, Ryan, Merkel, Olaf, Bilban, Martin, Hofbauer, Sebastian, Kim, Soojin, Addison, Joseph, Zou, Jie, Ji, Chunyan, Bunting, Silvia T., Wang, Zhengqi, Shoham, Menachem, Huang, Gang, Bago-Horvath, Zsuzsanna, Gibson, Laura F., Rojanasakul, Yon, Remick, Scot, Ivanov, Alexey, Pugacheva, Elena, Bunting, Kevin D., Moriggl, Richard, Kenner, Lukas, Tse, William
Publicado no Oncotarget (2015)