Reelin protects against amyloid β toxicity in vivo

Alzheimer's disease (AD) is a currently incurable neurodegenerative disorder and the most common form of dementia in people over the age of 65. The predominant genetic risk factor for AD is the ε4 allele encoding apolipoprotein E (ApoE4). The secreted glycoprotein Reelin, which is a physiologic...

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Détails bibliographiques
Publié dans:Sci Signal
Auteurs principaux: Lane-Donovan, Courtney, Philips, Gary T., Wasser, Catherine R., Durakoglugil, Murat S., Masiulis, Irene, Upadhaya, Ajeet, Pohlkamp, Theresa, Coskun, Cagil, Kotti, Tiina, Steller, Laura, Hammer, Robert E., Frotscher, Michael, Bock, Hans H., Herz, Joachim
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652952/
https://ncbi.nlm.nih.gov/pubmed/26152694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa6674
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