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Efnb's do not affect canonical Reelin signaling

Reeler mice exhibit loss of the signaling protein Reelin (Reln) which affects radial pyramidal neuron migration and results in cortical layer malformation(1). During cortical development Eph receptor/ephrin ligand (Eph/Efn) cell-cell interactions are important for neuronal migration, axonal/dendriti...

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Foilsithe in:Nature
Main Authors: Pohlkamp, Theresa, Xiao, Lei, Sultana, Rukhsana, Bepari, Asim, Bock, Hans H., Henkemeyer, Mark, Herz, Joachim
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546907/
https://ncbi.nlm.nih.gov/pubmed/27882975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20129
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