Reelin protects against amyloid β toxicity in vivo

Alzheimer's disease (AD) is a currently incurable neurodegenerative disorder and the most common form of dementia in people over the age of 65. The predominant genetic risk factor for AD is the ε4 allele encoding apolipoprotein E (ApoE4). The secreted glycoprotein Reelin, which is a physiologic...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Lane-Donovan, Courtney, Philips, Gary T., Wasser, Catherine R., Durakoglugil, Murat S., Masiulis, Irene, Upadhaya, Ajeet, Pohlkamp, Theresa, Coskun, Cagil, Kotti, Tiina, Steller, Laura, Hammer, Robert E., Frotscher, Michael, Bock, Hans H., Herz, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652952/
https://ncbi.nlm.nih.gov/pubmed/26152694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa6674
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