Reelin protects against amyloid β toxicity in vivo

Alzheimer's disease (AD) is a currently incurable neurodegenerative disorder and the most common form of dementia in people over the age of 65. The predominant genetic risk factor for AD is the ε4 allele encoding apolipoprotein E (ApoE4). The secreted glycoprotein Reelin, which is a physiologic...

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Udgivet i:Sci Signal
Main Authors: Lane-Donovan, Courtney, Philips, Gary T., Wasser, Catherine R., Durakoglugil, Murat S., Masiulis, Irene, Upadhaya, Ajeet, Pohlkamp, Theresa, Coskun, Cagil, Kotti, Tiina, Steller, Laura, Hammer, Robert E., Frotscher, Michael, Bock, Hans H., Herz, Joachim
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652952/
https://ncbi.nlm.nih.gov/pubmed/26152694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa6674
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