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Reelin signaling antagonizes β-amyloid at the synapse
Abnormal processing of the amyloid precursor protein (APP) and β-amyloid (Aβ) plaque accumulation are defining features of Alzheimer disease (AD), a genetically complex neurodegenerative disease that is characterized by progressive synapse loss and neuronal cell death. Aβ induces synaptic dysfunctio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747222/ https://ncbi.nlm.nih.gov/pubmed/19805234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908176106 |
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