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Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning
Apoer2 is an essential receptor in the central nervous system that binds to the apolipoprotein ApoE. Various splice variants of Apoer2 are produced. We showed that Apoer2 lacking exon 16, which encodes the O-linked sugar (OLS) domain, altered the proteolytic processing and abundance of Apoer2 in cel...
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| Gepubliceerd in: | Sci Signal |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355955/ https://ncbi.nlm.nih.gov/pubmed/25429077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005438 |
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