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The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease

The LDL receptor (LDLR) family has long been studied for its role in cholesterol transport and metabolism; however, the identification of ApoE4, an LDLR ligand, as a genetic risk factor for late-onset Alzheimer’s disease has focused attention on the role this receptor family plays in the CNS. Surpri...

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Détails bibliographiques
Publié dans:J Lipid Res
Auteurs principaux: Lane-Donovan, Courtney, Herz, Joachim
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454520/
https://ncbi.nlm.nih.gov/pubmed/28292942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R075507
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