Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning

Apoer2 is an essential receptor in the central nervous system that binds to the apolipoprotein ApoE. Various splice variants of Apoer2 are produced. We showed that Apoer2 lacking exon 16, which encodes the O-linked sugar (OLS) domain, altered the proteolytic processing and abundance of Apoer2 in cel...

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Detaylı Bibliyografya
Yayımlandı:Sci Signal
Asıl Yazarlar: Wasser, Catherine R., Masiulis, Irene, Durakoglugil, Murat S., Lane-Donovan, Courtney, Xian, Xunde, Beffert, Uwe, Agarwala, Anandita, Hammer, Robert E., Herz, Joachim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355955/
https://ncbi.nlm.nih.gov/pubmed/25429077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005438
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