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Different types of interaction between PCNA and PIP boxes contribute to distinct cellular functions of Y-family DNA polymerases
Translesion DNA synthesis (TLS) by the Y-family DNA polymerases Polη, Polι and Polκ, mediated via interaction with proliferating cell nuclear antigen (PCNA), is a crucial pathway that protects human cells against DNA damage. We report that Polη has three PCNA-interacting protein (PIP) boxes (PIP1, 2...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652755/ https://ncbi.nlm.nih.gov/pubmed/26170230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv712 |
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