Relevance of Simultaneous Mono-Ubiquitinations of Multiple Units of PCNA Homo-Trimers in DNA Damage Tolerance

DNA damage tolerance (DDT) pathways, including translesion synthesis (TLS) and additional unknown mechanisms, enable recovery from replication arrest at DNA lesions. DDT pathways are regulated by post-translational modifications of proliferating cell nuclear antigen (PCNA) at its K164 residue. In pa...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kanao, Rie, Masuda, Yuji, Deguchi, Saori, Yumoto-Sugimoto, Mayumi, Hanaoka, Fumio, Masutani, Chikahide
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332867/
https://ncbi.nlm.nih.gov/pubmed/25692884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118775
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