UV-B Radiation Induces Epithelial Tumors in Mice Lacking DNA Polymerase η and Mesenchymal Tumors in Mice Deficient for DNA Polymerase ι

DNA polymerase η (Pol η) is the product of the Polh gene, which is responsible for the group variant of xeroderma pigmentosum, a rare inherited recessive disease which is characterized by susceptibility to sunlight-induced skin cancer. We recently reported in a study of Polh mutant mice that Pol η i...

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Bibliografiske detaljer
Main Authors: Ohkumo, Tsuyoshi, Kondo, Yuji, Yokoi, Masayuki, Tsukamoto, Tetsuya, Yamada, Ayumi, Sugimoto, Taiki, Kanao, Rie, Higashi, Yujiro, Kondoh, Hisato, Tatematsu, Masae, Masutani, Chikahide, Hanaoka, Fumio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636855/
https://ncbi.nlm.nih.gov/pubmed/17015482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01076-06
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