Relevance of Simultaneous Mono-Ubiquitinations of Multiple Units of PCNA Homo-Trimers in DNA Damage Tolerance

DNA damage tolerance (DDT) pathways, including translesion synthesis (TLS) and additional unknown mechanisms, enable recovery from replication arrest at DNA lesions. DDT pathways are regulated by post-translational modifications of proliferating cell nuclear antigen (PCNA) at its K164 residue. In pa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kanao, Rie, Masuda, Yuji, Deguchi, Saori, Yumoto-Sugimoto, Mayumi, Hanaoka, Fumio, Masutani, Chikahide
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332867/
https://ncbi.nlm.nih.gov/pubmed/25692884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118775
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