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Linker histone H1.2 establishes chromatin compaction and gene silencing through recognition of H3K27me3

Linker histone H1 is a protein component of chromatin and has been linked to higher-order chromatin compaction and global gene silencing. However, a growing body of evidence suggests that H1 plays a gene-specific role, regulating a relatively small number of genes. Here we show that H1.2, one of the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Jin-Man, Kim, Kyunghwan, Punj, Vasu, Liang, Gangning, Ulmer, Tobias S., Lu, Wange, An, Woojin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652225/
https://ncbi.nlm.nih.gov/pubmed/26581166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16714
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