Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing

The N-terminal tail of histone H2B is believed to be involved in gene silencing, but how it exerts its function remains elusive. Here, we report the biochemical characterization of p14ARF tumor suppressor as a transcriptional repressor that selectively recognizes the unacetylated H2B tails on nucleo...

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Библиографические подробности
Главные авторы: Choi, Jongkyu, Kim, Hyunjung, Kim, Kyunghwan, Lee, Bomi, Lu, Wange, An, Woojin
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
Предметы:
Gene Regulation, Chromatin and Epigenetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241654/
https://ncbi.nlm.nih.gov/pubmed/21846774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr642
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