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Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing
The N-terminal tail of histone H2B is believed to be involved in gene silencing, but how it exerts its function remains elusive. Here, we report the biochemical characterization of p14ARF tumor suppressor as a transcriptional repressor that selectively recognizes the unacetylated H2B tails on nucleo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241654/ https://ncbi.nlm.nih.gov/pubmed/21846774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr642 |
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