p53 Requires an Intact C-Terminal Domain for DNA Binding and Transactivation

The p53 tumor suppressor plays a critical role in mediating cellular response to a wide range of environmental stresses. p53 regulates these processes mainly by acting as a short-lived DNA binding protein that stimulates transcription from numerous genes involved in cell cycle arrest, programmed cel...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Hyunjung, Kim, Kyunghwan, Choi, Jongkyu, Heo, Kyu, Baek, Hwa Jin, Roeder, Robert G., An, Woojin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267882/
https://ncbi.nlm.nih.gov/pubmed/22178617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.001
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