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p53 Requires an Intact C-Terminal Domain for DNA Binding and Transactivation
The p53 tumor suppressor plays a critical role in mediating cellular response to a wide range of environmental stresses. p53 regulates these processes mainly by acting as a short-lived DNA binding protein that stimulates transcription from numerous genes involved in cell cycle arrest, programmed cel...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3267882/ https://ncbi.nlm.nih.gov/pubmed/22178617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.001 |
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