The accumulation mechanism of the hypoxia imaging probe “FMISO” by imaging mass spectrometry: possible involvement of low-molecular metabolites

(18)F-fluoromisonidazole (FMISO) has been widely used as a hypoxia imaging probe for diagnostic positron emission tomography (PET). FMISO is believed to accumulate in hypoxic cells via covalent binding with macromolecules after reduction of its nitro group. However, its detailed accumulation mechani...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Masaki, Yukiko, Shimizu, Yoichi, Yoshioka, Takeshi, Tanaka, Yukari, Nishijima, Ken-ichi, Zhao, Songji, Higashino, Kenichi, Sakamoto, Shingo, Numata, Yoshito, Yamaguchi, Yoshitaka, Tamaki, Nagara, Kuge, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652161/
https://ncbi.nlm.nih.gov/pubmed/26582591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16802
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados