Elimination of tumor hypoxia by eribulin demonstrated by (18)F-FMISO hypoxia imaging in human tumor xenograft models

BACKGROUND: Eribulin, an inhibitor of microtubule dynamics, shows antitumor potency against a variety of solid cancers through its antivascular activity and remodeling of tumor vasculature. (18)F-Fluoromisonidazole ((18)F-FMISO) is the most widely used PET probe for imaging tumor hypoxia. In this st...

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Dettagli Bibliografici
Pubblicato in:EJNMMI Res
Autori principali: Zhao, Songji, Yu, Wenwen, Ukon, Naoyuki, Tan, Chengbo, Nishijima, Ken-ichi, Shimizu, Yoichi, Higashikawa, Kei, Shiga, Tohru, Yamashita, Hiroko, Tamaki, Nagara, Kuge, Yuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2019
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546772/
https://ncbi.nlm.nih.gov/pubmed/31161539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-019-0521-x
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