Dual tracer evaluation of dynamic changes in intratumoral hypoxic and proliferative states after radiotherapy of human head and neck cancer xenografts using radiolabeled FMISO and FLT

BACKGROUND: Radiotherapy is an important treatment strategy for head and neck cancers. Tumor hypoxia and repopulation adversely affect the radiotherapy outcome. Accordingly, fractionated radiotherapy with dose escalation or altered fractionation schedule is used to prevent hypoxia and repopulation....

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Main Authors: Fatema, Chowdhury Nusrat, Zhao, Songji, Zhao, Yan, Yu, Wenwen, Nishijima, Ken-ichi, Yasuda, Koichi, Kitagawa, Yoshimasa, Tamaki, Nagara, Kuge, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179856/
https://ncbi.nlm.nih.gov/pubmed/25245041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-692
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