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Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate
Liver X receptor (LXR) agonists have been explored as potential treatments for atherosclerosis and other diseases based on their ability to induce reverse cholesterol transport and suppress inflammation. However, this therapeutic potential has been hindered by on-target adverse effects in the liver...
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| Publicado en: | Bioconjug Chem |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4651790/ https://ncbi.nlm.nih.gov/pubmed/25945727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00203 |
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