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Poly(ethylenimine) conjugated bioreducible dendrimer for efficient gene delivery

Branched poly(ethylenimine) (PEI) 25 kDa is an efficient gene delivery vector with outstanding gene condensation ability and great endosome escape activity. However, it also induces higher cytotoxicity. Transfection efficiency and toxicity of PEI are highly dependent upon their molecular weight and...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Nam, Kihoon, Jung, Simhyun, Nam, Joung-Pyo, Kim, Sung Wan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688073/
https://ncbi.nlm.nih.gov/pubmed/26551343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.11.005
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