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Poly(ethylenimine) conjugated bioreducible dendrimer for efficient gene delivery

Branched poly(ethylenimine) (PEI) 25 kDa is an efficient gene delivery vector with outstanding gene condensation ability and great endosome escape activity. However, it also induces higher cytotoxicity. Transfection efficiency and toxicity of PEI are highly dependent upon their molecular weight and...

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Pubblicato in:J Control Release
Autori principali: Nam, Kihoon, Jung, Simhyun, Nam, Joung-Pyo, Kim, Sung Wan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688073/
https://ncbi.nlm.nih.gov/pubmed/26551343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.11.005
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