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Poly(ethylenimine) conjugated bioreducible dendrimer for efficient gene delivery
Branched poly(ethylenimine) (PEI) 25 kDa is an efficient gene delivery vector with outstanding gene condensation ability and great endosome escape activity. However, it also induces higher cytotoxicity. Transfection efficiency and toxicity of PEI are highly dependent upon their molecular weight and...
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| Veröffentlicht in: | J Control Release |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4688073/ https://ncbi.nlm.nih.gov/pubmed/26551343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.11.005 |
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