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Paradoxical Effects of Partial Leptin Deficiency on Bone in Growing Female Mice

Morbidly obese, leptin-deficient ob/ob mice display low bone mass, mild osteoclast-rich osteopetrosis, and increased bone marrow adiposity. While partial leptin deficiency results in increased weight, the skeletal manifestations of partial leptin deficiency are less well defined. We therefore analyz...

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Detalhes bibliográficos
Publicado no:Anat Rec (Hoboken)
Main Authors: Philbrick, Kenneth A., Turner, Russell T., Branscum, Adam J., Wong, Carmen P., Iwaniec, Urszula T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651779/
https://ncbi.nlm.nih.gov/pubmed/26370912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ar.23267
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