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Leptin Stimulates Bone Formation in ob/ob Mice at Doses Having Minimal Impact on Energy Metabolism

Leptin, the protein product of the ob gene, is essential for normal bone growth, maturation, and turnover. Peripheral actions of leptin occur at lower serum levels of the hormone than central actions because entry of leptin into the central nervous system (CNS) is limited due to its saturable transp...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Philbrick, Kenneth A., Wong, Carmen P., Branscum, Adam J., Turner, Russell T., Iwaniec, Urszula T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288125/
https://ncbi.nlm.nih.gov/pubmed/28057869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0484
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