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Leptin Increases Particle-Induced Osteolysis in Female ob/obMice
Particles generated from wear of prosthesis joint bearing surfaces induce inflammation-mediated periprosthetic bone resorption (osteolysis). Morbidly obese leptin-deficient ob/ob mice are resistant to polyethylene particle-induced bone loss, suggesting that leptin, a hormone produced by adipocytes t...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6172200/ https://ncbi.nlm.nih.gov/pubmed/30287858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33173-9 |
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