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Morbid Obesity Attenuates the Skeletal Abnormalities Associated with Leptin Deficiency in Mice

Leptin-deficient ob/ob mice are morbidly obese and exhibit low total bone mass and mild osteopetrosis. In order to disassociate the skeletal effects of leptin deficiency from those associated with morbid obesity, we evaluated bone mass, architecture, gene expression, and indices of bone turnover in...

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Detalhes bibliográficos
Main Authors: Turner, Russell T., Philbrick, Kenneth A., Wong, Carmen P., Olson, Dawn A., Branscum, Adam J., Iwaniec, Urszula T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161659/
https://ncbi.nlm.nih.gov/pubmed/24990938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-14-0224
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