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Morbid Obesity Attenuates the Skeletal Abnormalities Associated with Leptin Deficiency in Mice
Leptin-deficient ob/ob mice are morbidly obese and exhibit low total bone mass and mild osteopetrosis. In order to disassociate the skeletal effects of leptin deficiency from those associated with morbid obesity, we evaluated bone mass, architecture, gene expression, and indices of bone turnover in...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4161659/ https://ncbi.nlm.nih.gov/pubmed/24990938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-14-0224 |
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