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Structure of Liver Receptor Homolog-1 (NR5A2) with PIP(3) hormone bound in the ligand binding pocket

The nuclear receptor LRH-1 (Liver Receptor Homolog-1, NR5A2) is a transcription factor that regulates gene expression programs critical for many aspects of metabolism and reproduction. Although LRH-1 is able to bind phospholipids, it is still considered an orphan nuclear receptor (NR) with an unknow...

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Dettagli Bibliografici
Pubblicato in:J Struct Biol
Autori principali: Sablin, Elena P., Blind, Raymond D., Uthayaruban, Rubatharshini, Chiu, HJ, Deacon, Ashley M., Das, Debanu, Ingraham, Holly A., Fletterick, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651778/
https://ncbi.nlm.nih.gov/pubmed/26416531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2015.09.012
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