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Direct modification and regulation of a nuclear receptor-PIP(2) complex by the nuclear inositol-lipid kinase IPMK

Phosphatidylinositol (4,5)-bisphosphate (PIP(2)) is best known as a plasma membrane-bound regulatory lipid. While PIP(2) and phosphoinositide-modifying enzymes coexist in the nucleus, their roles in the nucleus remain unclear. Here we show that the nuclear inositol polyphosphate multikinase (IPMK),...

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Bibliographische Detailangaben
Hauptverfasser: Blind, Raymond D., Suzawa, Miyuki, Ingraham, Holly A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395721/
https://ncbi.nlm.nih.gov/pubmed/22715467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003111
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