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Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

Despite the fact that many nuclear receptors are ligand dependent, the existence of obligate regulatory ligands is debated for some receptors, including steroidogenic factor 1 (SF-1). Although fortuitously bound bacterial phospholipids were discovered in the structures of the SF-1 ligand-binding dom...

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Detalhes bibliográficos
Main Authors: Sablin, Elena P., Blind, Raymond D., Krylova, Irina N., Ingraham, Jared G., Cai, Fang, Williams, Jon D., Fletterick, Robert J., Ingraham, Holly A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646595/
https://ncbi.nlm.nih.gov/pubmed/18988706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0508
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