Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons

Many neuropathological and experimental studies suggest that the degeneration of dopaminergic terminals and axons precedes the demise of dopaminergic neurons in the substantia nigra, which finally results in the clinical symptoms of Parkinson disease (PD). The mechanisms underlying this early axonal...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Koch, J C, Bitow, F, Haack, J, d'Hedouville, Z, Zhang, J-N, Tönges, L, Michel, U, Oliveira, L M A, Jovin, T M, Liman, J, Tatenhorst, L, Bähr, M, Lingor, P
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650722/
https://ncbi.nlm.nih.gov/pubmed/26158517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.169
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