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ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS

The Rho/ROCK/LIMK pathway is central for the mediation of repulsive environmental signals in the central nervous system. Several studies using pharmacological Rho-associated protein kinase (ROCK) inhibitors have shown positive effects on neurite regeneration and suggest additional pro-survival effec...

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Autors principals: Koch, J C, Tönges, L, Barski, E, Michel, U, Bähr, M, Lingor, P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047920/
https://ncbi.nlm.nih.gov/pubmed/24832597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.191
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